P145 IVABRADINE IN TETRALOGY OF FALLOT AND POSTOPERATIVE JUNCTIONAL ECTOPIC TACHYCARDIA

Abstract Introduction Ivabradine is a selective inhibitor of sodium’s If current; it acts at the level sinus node causing bradycardizing effect without on inotropism and atrioventricular conduction. In fact, channel, located in pacemaker cells, activated hyperpolarization allows membrane potential to become gradually more positive until threshold reached. Previous studies have actually shown usefulness ivabradine not only for slowing rate but also case atrial tachycardia ectopic junctional tachycardia. Case report: Our patient, suffering tetralogy Fallot, undergoes transannular patch correction surgery age 6 months. During stay postoperative intensive care presents numerous episodes Therapy with amiodarone ev undertaken, discrete response; ECG, frequent isolated repetitive supraventricular extrasystoles (pairs triplets) are observed. After infusion oral therapy beta–blocker associated, obtaining good rhythm control. addition, presence sustained high frequency arrhythmia affects hemodynamic parameters child. For persistence arrhythmic episodes, undertaken dose 0.05 mg/kg orally twice day. Stable observed, so subsequently discontinued continued. No arrhythmias observed either during hospitalization or subsequent follow–up after discharge, carried out seriated Holter ECGs. about 3 months, discontinued, absence ventricular arrhythmias. Conclusions sodium channel cells; born as drug its action node, has been demonstrated treatment due enhanced automatism reentry. It is, therefore, conceivable channels foci, which would allow use real antiarrhythmic drug, exploiting peculiar interfering atrium intraventricular